Probable Cortico-basal Syndrome
نویسندگان
چکیده
منابع مشابه
Functional immaturity of cortico-basal ganglia networks in Gilles de la Tourette syndrome.
Gilles de la Tourette syndrome is a clinically heterogeneous disorder with poor known pathophysiology. Recent neuropathological and structural neuroimaging data pointed to the dysfunction of cortico-basal ganglia networks. Nonetheless, it is not clear how these structural changes alter the functional activity of the brain and lead to heterogeneous clinical expressions of the syndrome. The objec...
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We report an unusual case of probable progressive multifocal leukoencephalopathy (PML), who initially presented with a right-sided movement disorder, including upper limb dystonia, tremor, and dyspraxia, reminiscent of corticobasal degeneration. In the further course, the patient developed disorientation, confusion, and bradyphrenia. The appearance of white matter MRI lesions as well as a posit...
متن کاملThe Behavioural Neurology of Basal Ganglia Disorders
Basal ganglia disorders are common clinical conditions characterised by specific motor dysfunction and associated behavioral problems. The underlying pathophysiology primarily consists in alterations of the cortico-striato-thalamo-cortical pathways, which can be related to both neurodegenerative pathology (e.g. Parkinson disease, Huntington disease) and neurodevelopmental processes (e.g. Touret...
متن کاملStriatal cholinergic interneurons and cortico-striatal synaptic plasticity in health and disease.
Basal ganglia disorders such as Parkinson's disease, dystonia, and Huntington's disease are characterized by a dysregulation of the basal ganglia neuromodulators (dopamine, acetylcholine, and others), which impacts cortico-striatal transmission. Basal ganglia disorders are often associated with an imbalance between the midbrain dopaminergic and striatal cholinergic systems. In contrast to the e...
متن کاملAltered structural connectivity of cortico-striato-pallido-thalamic networks in Gilles de la Tourette syndrome
Gilles de la Tourette syndrome is a childhood-onset syndrome characterized by the presence and persistence of motor and vocal tics. A dysfunction of cortico-striato-pallido-thalamo-cortical networks in this syndrome has been supported by convergent data from neuro-pathological, electrophysiological as well as structural and functional neuroimaging studies. Here, we addressed the question of str...
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